ADME LIMS will accelerate data reporting at QPS

01/11/2010

The newest customer for Debra, LabLogic’s LIMS for absorption, distribution, metabolism and excretion studies (ADME), is GLP/GCP-compliant contract research organisation QPS, which recently installed the latest 5.7.8 version at its Newark, Delaware facility.

Ben Chien, PhD, QPS chairman, president and CEO said: "Studies determining ADME patterns in laboratory animals and humans are an integral part of our drug metabolism and pharmacokinetics services, and, as a quality initiative, we have been actively integrating radio-labelled mass balance /excretion and tissue distribution by Quantitative Whole-Body Autoradiography under one study protocol. This allows us to start on the companion metabolite profiling and identification studies in a shorter time frame."

"The addition of Debra will increase our competitive advantage and allow us to report high quality data even more quickly to our sponsors."

Huw Loaring, systems director at LabLogic added: "Contract research organisations (CROs) see big returns from the time savings achieved using Debra for their ADME studies, especially in terms of reporting and data checking."

"Increasingly, many pharmaceutical customers are using turnkey ADME solution providers like QPS - not just for their in vivo studies, but also for radiochromatography on their samples and the ensuing determination of key metabolites. We are excited by the new tools coming early next year to allow CROs to share data back to their sponsors, which will allow them to understand human biotransformation pathways of their drug candidates at a very early stage of development. The latter is extremely important not only in terms of identifying MIST-triggering metabolites, but also because it supports bio-waiver applications."