Radiation protection for emerging Targeted Alpha Therapies

16/04/2026

An example of a customized workstation installed at a research facility that handles ²²⁵Ac.

At a glance

> Targeted Alpha Therapies present inherent radiation risks to facilities working in this rapidly growing area of clinical research.

> BriTec – a sister company of LabLogic – is a specialist manufacturer of bespoke shielding solutions for those working with sources of ionizing radiation, including alpha-emitters.

> Workstations, dispensing units and cabinets can be customized to exact specifications, allowing new or existing facilities to be safeguarded.

BriTec’s shielding solutions allow facilities to safely handle alpha-emitting radionuclides

The rise of Targeted Alpha Therapies (TAT) is opening up promising new pathways for treating many critical illnesses, including cancers. But using powerful alpha-emitting radionuclides such as ²²⁵Ac, ²¹¹At, and ²¹²Pb present unique challenges for facilities handling, dispensing, and storing them due to complex decay chains and associated radiation.

Although many alpha-emitting radionuclides such as ²²⁵Ac emit gammas during decay from daughters including ²²¹Fr and ²¹³Bi, the emissions are generally low in abundance. Nonetheless, appropriate shielding is critical to ensure staff safety.

Customized shielding for all energies

LabLogic has partnered with BriTec, a specialist manufacturer of shielded solutions for radiation protection. With many years of experience supplying medical and research facilities working with radioisotopes for diagnostics and therapies, BriTec has developed extensive expertise in shielding against gamma-emitting radionuclides and other higher energy isotopes – expertise that can now be applied to new alpha therapeutics.

For isotopes such as ²¹²Pb which emit high-energy gammas, BriTec can supply customized shielding designed specifically to your requirements to safeguard against these.

Complete project management from design to installation

BriTec has supplied both new facilities and existing ones undergoing refurbishment, collaborating closely with contractors to manage projects from concept to completion. As Targeted Alpha Therapies move from research to clinical use, it is critically important for sites to be futureproofed. As a specialist manufacturer, BriTec can supply any bespoke designs built to precise end-user specifications, including:

Workstations for safe handling and dispensing of alpha emitters.
Storage units for securely storing radioactive materials such as lockable safes, cabinets and waste containers.
Customized units tailored to exact dimensions to maximise space and optimise working arrangements.

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