Hidex 300 SL paves the way for groundbreaking obesity research
9 March 2018
300 SL plays central role in key diabetes research
A Boston University group working in the area of obesity research have recently published a paper using the Hidex 300 SL Liquid Scintillation Counter. It is known that both genetic predispositions and environmental factors may lead to a development of type 1 diabetes. However, there is still a lack of understanding into how triggers in the autoimmune response can lead to to the development of the disease.
Research has already been done in detail on the molecular level at how it triggers the immune system into destroying the body’s own cells that produce insulin within the pancreas. This paper investigates even further into how type 1 diabetes alters lipid handling and metabolism.
Liquid scintillation counter used to measure β particles
As part of the study the 300 SL was used by the group to measure β particle emissions, therefore calculating fatty acid oxidation of fibroblast cells from subjects both with and without type 1 diabetes. They found that in fact subjects with the disease did handle fatty acid differently which ultimately does alter lipid handling and the metabolism in the individuals with type 1 diabetes.
These results were also backed-up by the outcomes of other experimental methods done as part of the study. This therefore shows that the 300 SL liquid scintillation counter is a reliable and accurate instrument in performing liquid scintillation for this study and future studies.