1 instrument, 2 clicks, 3 QC tests
27/03/2025
At a glance
> Laura Radiopharma’s Nuclide ID function is now compatible with the Scan-RAM 2 using an MCA.
> Instead of manually inputting dose calibrator readings into spreadsheets, it provides real-time decay monitoring with measurements every second.
> This means the Scan-RAM 2 can now perform radiochemical purity, acquire gamma spectra, and measure decay for half-life determination in a single, compliant run.
Half-life measurement with radio-TLC scanning
LabLogic recently announced a new Nuclide ID function in Laura Radiopharma. This allows users to test radionuclidic identification via a half-life measurement while simultaneously acquiring gamma spectra using the Spec-RAM series of gamma spectrometers. We are now pleased to announce this new feature has been expanded and is now compatible with the Scan-RAM 2 radio-TLC scanner with an MCA.
The old way of doing things
Radionuclide identification is a key Quality Control test usually performed using a dose calibrator with measurements taken every 10 – 15 minutes. Typically, measurements are manually input into a spreadsheet to calculate the half-life, but this means data is not GMP compliant and lacks traceability. Furthermore, dose dispensing is prioritised over QC testing, meaning delays are introduced when waiting for the dose calibrator to be available.
Measuring decay every single second
Using a Scan-RAM 2 or a Spec-RAM, Laura can acquire a gamma spectrum and simultaneously plot the isotope’s decay by taking a measurement every single second. A visual representation of the decay is built up in real-time on the screen, and by providing hundreds of datapoints within minutes, users can determine radionuclidic ID quicker and faster.
Radiochemical purity, gamma spectrum, and half-life determination
What is so exciting about the Scan-RAM 2 is that it can perform three key tests in one run when controlled by Laura: radiochemical purity, gamma spectrum, and decay measurement for half-life determination. But how does this work?
Once the user clicks start in Laura, the Scan-RAM 2 will drive its detector carriage along the TLC plate for radiochemical purity. The carriage will then return to its original position and based on the peak(s) identified by Laura, the MCA will drive along the plate again and sit directly over the peak(s) to acquire the gamma spectrum and plot the decay curve simultaneously.
At the end of the run, the measured half-life and identified isotope will be displayed on screen with a percentage difference from the theoretical half-life. The results of all tests are then exported and presented in a single report.
Find out more
You can learn more about Laura Radiopharma’s Nuclide ID function by clicking the button below to speak to a product specialist directly.