The Hidex Sense wheel: 32 filter capacity, 1 compact microplate reader

02/10/2025

At a glance

> The microplate reader uses an innovative filter wheel system housing up to 32 filters for both excitation and emission, covering the full spectrum of wavelengths.

> With space for 22 optical filters and 8 custom filters, users can tailor the filter wheel to their requirements.

> The instrument combines the speed and sensitivity of a filter-based system with the flexibility of a monochromator.

Full wavelength coverage without manual filter handling

The Hidex Sense microplate reader uses an innovative filter wheel system housing up to 32 filters which cover both excitation and emission. This automated storage provides full wavelength coverage without the need for manual filter handling, making it an ideal instrument for shared laboratory environments with multiple users.

Traditionally, microplate readers have been either monochromatic or filter-based, each offering distinct advantages. The Sense uniquely combines both approaches. Its extended filter wheel offers the speed and sensitivity of a filter-based system, while maintaining the flexibility of a monochromator.

Custom filters for custom research

The advanced filter set includes 22 optical filters, covering a broad spectrum from infrared to luminescence, with room for 8 additional custom filters. The Sense’s design and intuitive software mean users can load new filters into the wheel directly through the front of the instrument, removing the need for an engineer or dismantling the unit.

This innovative design not only makes fluorescent readings more efficient but also delivers higher-quality data. Additionally, the Sense improves reading through:

  • Top and bottom reading for greater assay flexibility
  • Automatic focus adjustment for precision
  • Aperture and dichroic beam splitter selection
  • Fibreless optics to eliminate sensitivity compromises

Ultrafast absorbance spectral readout

The system also delivers ultrafast absorbance spectral readout using a high sensitivity CCD spectrograph, scanning the full UV to IR spectrum in under a second per well, or capturing up to 10 discrete wavelengths simultaneously.

Supporting all major non-radioactive detection modes, the Hidex Sense allows:

  • Fluorescence intensity, FRET, and dual excitation
  • Absorbance spectral read
  • Filter luminescence and BRET
  • Time-resolved fluorescence and TR-FRET
  • Fluorescence polarization
  • AlphaScreen®/AlphaLISA® (optional)

Find out more

You can find out more about the Hidex Sense and its innovative filter wheel by clicking the button below to speak to a product specialist directly.

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