TLC/HPLC system assists imaging chemistry research group

8 December 2008

A compact and versatile system from LabLogic is meeting the radiochromatography detection needs of the Imaging Chemistry research group at King's College London.

The group's laboratory at St Thomas' Hospital has a Mini-Scan radio-TLC scanner and Flow-Count radio-HPLC flow-through monitor.

"We explore new biological targets for molecular imaging and develop a wide variety of new radiopharmaceutical chemistry for PET and gamma imaging in cancer, heart disease and radionuclide therapy of cancer, so radiochromatography is central to most of our activities," says Professor of Imaging Chemistry Phil Blower.

"The research laboratory has two LabLogic systems combining radio-TLC scanning and radio-HPLC. We chose them because they share can the same detector and data analysis platform, saving space and reducing cost, and because of the joint support and compatibility of HPLC and radiation measurement by Agilent and LabLogic."

The Mini-Scan can detect on narrow strips and plates all of the commonly used isotopes in nuclear medicine, radiopharmacy and PET. It can accept up to six different detectors for a wide range of radionuclides from 32P up to 99mTc, 18F and others.

Flow-Count eliminates the need for fraction collecting and scintillation counting, offering a wide range of count rate, shielding and detection configurations in a single system. It can operate remotely up to 12 feet away from the base unit.

Laura, the industry's leading radiochromatography package for data collection and analysis, is under constant development to ensure its connectivity. Currently, it can control more than 100 HPLC and liquid handling modules.

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