Radio-HPLC in one simple solution
17 July 2024
At a glance
> In this new video, Product Specialist George Hunter walks us through the new, updated Logi-CHROM ONE.
> It provides a more accessible solution for radiochemical purity testing for facilities where bench space and funding may be prohibitive for traditional HPLC.
> Designed to be simple and streamlined, it is a plug-and-play system with limited connections to reduce training and validation efforts.
The alternative to traditional HPLC
The proliferation of nuclear medicine to diagnose and treat a range of illnesses has seen many older facilities retrospectively fitted with QC equipment to provide new therapies, meaning bench space is often restricted. The recently updated Logi-CHROM ONE is a small, simple solution for radio-HPLC that provides a light, cost-effective alternative to traditional HPLC stacks.
The new model improves usability by introducing a split-door design for easy access when loading samples, and the cabinet’s status LEDs provides users with a quick visual indicator as to the unit’s operational status. It has been designed specifically to be easier and quicker to setup and maintain, being a plug-and-play system with limited connections.
What’s inside?
Because the Logi-CHROM ONE is an integrated system as opposed to several modules stacked together, training and validation requirements are significantly reduced. It combines the most common HPLC modules into a single, all-in-one solution and features:
> Low-pressure gradient quaternary pump to deliver and blend up to four solvents.
> Integrated UV detector, commonly used for cold chromatography.
> Manual sample loader with injection actuated electronically to deliver superb sample integrity for maximum efficiency and accuracy. Options for sample injection are available through an automated switching valve and autosampler.
> Radioactivity detector based on our proven Flow-RAM 2 with three options available.
Your choice of radioactivity detector
Each of the radioactivity detector’s options allows you to configure the Logi-CHROM ONE to your requirements. Whether you’re using common gamma-emitters such as 99mTc or 18F, or weaker ones like 125I, there are suitable choices for all.
> 1” NaI(TI) scintillation detector for detecting gamma-emitting radionuclides in the energy range 20 keV to 1.5 MeV.
> 2” NaI(TI) scintillation detector for detecting gamma-emitting radionuclides in the energy range 30 keV to 3 MeV.
> 4π NaI(TI) well-type scintillation detector for detecting lower energy gammas using almost complete solid angle coverage.
A single point of control
Like all LabLogic instruments and many others, the Logi-CHROM ONE is controlled by Laura Radiopharma, our software for instrument control and radiochromatography data analysis. By providing a single point of control for radio-TLC, GC, and gamma spectrometry, it delivers a consistent, reliable approach to reporting for radiopharmacies and nuclear medicine departments, with complete data integrity when used with our LIMS, PETra and SPECTra.
Find out more
You can learn more about the Logi-CHROM ONE by watching our latest video or clicking the button below to speak to a product specialist directly.