The innovative, flexible and compliant radio-TLC scanner and radio-HPLC detector

LabLogic’s combined PET/SPECT Radio-TLC Scanner and radio-HPLC detector, the innovative Dual Scan-RAM, is designed to meet the ever increasing demands of the modern laboratory.

Versatile and compact, the instrument is fully controlled by market leading radio chromatography package Laura for PET, providing accurate and reproducible results for radiochemical purity measurements.

Innovation

The Dual Scan-RAM has a range of innovative features including a motorised detector, unique TLC plate support beds and an adjustable collimator.

Compliance

As with all LabLogic products the Dual Scan-RAM has been designed to exceed regulatory requirements. Features such as a single power button, coupled with the industry standard Laura for PET software offers users the ultimate in compliance.

Flexibility

The Dual Scan-RAM is not only a TLC scanner, it's a unique combination of a radio-TLC scanner and a radio-HPLC detector. They both work independently yet simultaneously and offer users the ultimate flexibility whilst saving valuable laboratory space. With a wide range of detectors suitable for both low and high levels of radioactivity, the Dual Scan-RAM is an ideal PET/SPECT instrument.

Adjustable Collimator

The adjustable height of the collimator combined with different aperture slits, offers users the ultimate flexibility whether working with high or low levels of radioactivity.

A Range of Detectors

Suitable for PET, SPECT and Alpha radionuclides across a range of radioactivity levels.

Motorised Detector

The detector’s smooth motor operation eliminates the need to tape the TLC plate to the scanning bed, significantly reducing finger dose and ensuring positional reproducibility.

The detector does not require any operational tolerance, the space taken up by the Scan-RAM is the same as the footprint of the instrument.

Engraved Ruler

Facilitates confirmation of the TLC strip size and allows users to record this information in Laura for PET, thus optimizing their analysis time.

Intelligent Front End Display

Users are able to view instrument parameters and performance at a glance.

Single Power Button

The single power button and full software control allows only users with an appropriate access level to make changes to the operating parameters. A full audit trail of these changes is recorded.

TLC Plate Beds

The Scan-RAM is supplied with TLC plate support beds which are easily cleaned, conveniently stored and ideal for lowering finger exposure. Accommodating any size TLC strip up to 5 x 20 cm.

USB Interface

USB interface which provides; instrument control, HV supply, data transfer and electronics power supply.

Built-in Analog to Digital Converter

This Dual Scan-RAM feature converts analog signals from other detectors such as UV, ECD, etc., into digital for use within Laura for PET. Bringing all signals into one place.

Custom-Made Lead Shielding

In order to minimize background interference LabLogic provides a range of lead shielding to meet different requirements.

Laura for PET

Scan-RAM control, digital data collection, analysis and reporting. All achieved using the industry standard radiochromatography data system Laura for PET.

Laura for PET has been the recognised industry standard software for radiochromatography for more than 20 years. The latest evolution of Laura for PET features control of many of the world's leading HPLC and radio detector systems to provide a single point of control for the entire radiochromatography analysis

Laura for PET also features:

  • Half-life correction.
  • Seamless interface with PETra™.
  • Scalable solution from stand-alone to enterprise level.
  • GLP and 21 CFR part 11 compliance options.
  • Automatic peak finder.
  • Document management system.
  • Unique summary table function for data comparison.
  • Powerful reporting and analysis tools.

What is the Scan-RAM operating tolerance?

Because the detector sweeps the scanning bed, there is an operating tolerance requirement, and as such the required operating space is the same as the footprint of the instrument

Why do I need the TLC support beds?

These beds have been provided for your own safety and to minimize finger dose exposure.

Can I clean the TLC support beds?

Yes you can clean them with standard cleaning solutions.

Where do I store my TLC support beds?

The TLC support beds are stored underneath the instrument, in the built-in racks provided.

Can I use the same Scan-RAM for different radionuclides?

Yes you can. The Scan-RAM is available with a range of interchangeable detectors for different radionuclides and different levels of radioactivity.

What is the difference between Dual and Single Scan-RAM?

The Dual Scan-RAM is two instruments in one. It is a radio-TLC scanner and radio-HPLC detector. This instrument is ideal for customers who have to analyze their samples by both methods as it saves on capital expenditure and operating space.

The Single Scan-RAM, is radio-TLC scanner only that I used for radio-TLC analysis.

What is the size of the crystal in your detectors?

We offer a range of different crystal sizes to meet different requirements. If you know what radionuclides you will work with, LabLogic will furnish you with information on the recommended detector and crystal size.

What happens if a component stops working In the Dual Scan-RAM?

The electronics in the Dual Scan-RAM are separate for radio-TLC and radio-HPLC. In the unlikely event that one set of electronics develops a fault, the use of the radio-HPLC, or radio-TLC depending upon what happens, would not be affected.

Do you have to sellotape TLC strips to the scanning bed?

No you do not. The scanning bed is stationary and it is the detector that sweeps the bed. Also, your TLC strips are held by the TLC support beds which are locked in place by soft buttons.

How do I change the operating parameters?

All operating parameters are changed through Laura for PET software where a full audit trail of the changes is recorded.

Documents

Application Notes

Improved QC of radiopharmaceutcials with a dual-mode instrument for combined r-HPLC and r-TLC analysis
By: Deakin, Tom; Zahirovic, Elvir; Lowe, Jonathan; et al.
Conference: Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging Location: Baltimore, MD Date: JUN 06-10, 2015
Sponsor(s): Soc Nucl Med & Mol Imaging
JOURNAL OF NUCLEAR MEDICINE Volume: 56 Issue: 3 Supplement: 3 Meeting Abstract: 332 Published: MAY 1 2015