Did you know Debra can create a single report to show how metabolite concentrations and recoveries change over time?
09/12/2024
Keeping track of metabolite data over the course of a metabolism study can be challenging
Producing a final table to show individual component concentration or recovery data for a large number of chromatographic analyses requires consolidation of data, additional calculations, and judgement on which metabolites to report.
LabLogic's Debra is a Laboratory Information Management System designed specifically to manage the entire life cycle of a range of drug and environmental metabolism studies within a regulated environment. It links with Laura, our radiochromatography and instrument control software, to allow HPLC results to be transferred directly to Debra, where individual metabolite concentrations and recoveries are automatically calculated.
Debra’s new HPLC Summary Report further enhances this feature by reporting metabolite data over multiple HPLC runs in a single table. Results can be displayed as concentration, dose recovery or relative to total radioactive residue, depending on the application area. This feature makes it very simple to produce a single table that shows metabolite data for samples over different timepoints.
Metabolites can be automatically included or excluded from the report based on configurable threshold levels; this allows users to focus on the on the key metabolites of interest with minimal input.
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