Designed to meet the needs of laboratories processing large quantities of samples, the Hidex 600 SLe is a high throughput automatic TDCR liquid scintillation counter.

Hidex are excited to release the improved 600 SLe. It has retained the same intuitive software, operation, and performance as the existing 600 SL, including the unique TDCR detector, but has several improved key features.

The 600 SLe now features an optional QR code reader for compliant sample identification, with barcodes read directly from the vial cap to improve traceability from sample to result. A cooling conveyor is included, with samples cooled at 5°C or greater than below ambient room temperature in normal laboratory conditions. It has improved error handling with more descriptive error messages to facilitate troubleshooting and the detection chamber hood now slides back rather than needing to be lifted, allowing access to retrieve stuck vials.

The Hidex 600 SLe can be used in a 21 CFR part 11 compliant manner

The Hidex 600 SLe can be used in a 21 CFR part 11 compliant manner thanks to Laura software. The 600 SLe can now be validated to ensure accuracy and reliability. Time-stamped audit trails are generated automatically and cannot be modified, making it easier to track end-user activity. Also in line with 21 CFR regulations, each end-user will have a unique, secure ID login and password.

Proven technology

The Hidex 600 SLe uses the robust and unique triple-to-double coincidence ratio (TDCR) counting technology from the successful 300 SL series. Coupled with added sample capacity for over 500 small vials (or 210 large vials), the 600 SLe can process samples at a rate which will satisfy even the most demanding production schedule.

The instrument’s software allows the user to work with an unlimited number of methods and apply them to a sample using a simple ID or barcode number. Samples are loaded in racks and as they automatically pass through the system, the instrument can scan an identification label on the vial and apply the required method accordingly.

Hidex’s MikroWin software version 5.62 is fully compatible with Windows 11

Hidex is the only manufacturer of liquid scintillation counters whose software is fully compatible with Windows 11, Microsoft’s latest major release. Hidex’s MikroWin version 5.62 can be run on any external desktop, whereas other manufacturers use internal computers that are integrated into the liquid scintillation counter itself.

This can present problems if there is a fault with the internal computer, as it prevents the user from operating the instrument as well. Being able to use an external desktop to manage your instruments allows MikroWin software to be easily updated with new releases and is compatible with Microsoft’s latest security features introduced in Windows 11.

Optional Features

The Hidex 600 SLe is available with all the options of the standard model, such as powerful alpha/beta separation, low level PMT detectors, cooling unit, and internal Eu-152 reference source.

To learn more about liquid scintillation counting applications and techniques please visit Hidex’s Liquid Scintillation – Measuring Procedures, New Developments eBook.

Hidex 600 SLe Super Low-Level Liquid Scintillation Counting

The Hidex 600 SLe super low-level liquid scintillation counter is equipped with additional lead shielding, low-level PMT detectors, and an active guard detector for further background reduction.

Ideal for 3H in water measurements, other low-level environmental monitoring, radiocarbon dating and biofuel verification.

New Active Guard

The Active Guard is a separate scintillator detector which measures and subtracts real-time background radiation. The guard can be turned off for high energy samples and does not interfere with alpha/beta separation.

Existing Hidex 600 SL customers 

Click on the tabs below to find out more about our customers, and how they are using the Hidex 600 SL in their laboratories. 

Lancaster Environment Center, UK

Studying photosynthetic carbon fixation in plants

The 600 SL is being used to study photosynthetic carbon fixation in plants at the Lancaster Environment Center. The center is Lancaster University’s dedicated environmental research facility, bringing together academics and researchers from the fields of geography, environmental sciences, and biological sciences to address major global challenges.

Lecturer in Plant Biotechnology Dr. Douglas Orr has been working as part of a larger team to better understand the biochemistry of photosynthesis to identify ways to improve its efficiency. Ultimately, it is hoped to breed more sustainable, resilient, and productive crops to address future food supplies and counter farming challenges brought about by climate change.

Find out what Dr. Orr had to say about his research and the 600 SL's high throughput by clicking the button below.

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University of Manchester, UK

The new National Nuclear User Facility RADioactive waste Management and Environmental Remediation (NNUF RADER) laboratories are co-located at the University of Manchester and will support research into characterising and understanding the behaviour of radioactive species in engineered and natural environments.

Dr Anthony Stockdale is an Experimental Officer at NNUF RADER said: 

"We chose the Hidex 600 SL due to its lower reliance on computational corrections, a high level of engagement between us and the LabLogic product specialists, and whilst only a minor consideration,  it certainly helps that the Hidex instruments are aesthetically well designed." 

"It was essential that we could analyze at the lowest level possible so environmental levels can be detected above background, so the extra shielding of the low-level version was essential for us. The large capacity of the samples will be of significant benefit in the future as we increase the user base for the facility."

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University of Washington, Seattle, USA

Supporting the development of radiopharmaceuticals for targeted alpha therapy

Michael J. Zittle is the Radioactive Materials Compliance Manager and Radiation Safety Officer at the University of Washington in Seattle. Mike has been using the Hidex 600 SL to maintain compliance and safety at the university and its three attached medical centers. We contacted him to see how he is planning to use the 600 SL in the development of radiopharmaceuticals for targeted alpha therapy.

Alpha/beta separation

“Something I really want to get into with the Hidex is alpha/beta separation, because we have some groups here at the university working with targeted alpha therapy (TAT) radionuclides using Actinium-225 and Astatine-211, and that’s really the future. These particular radionuclides emit alpha particles that pack a big punch when it comes to killing cancer cells internally, compared to external gamma rays.

“Being able to detect and separate alphas and betas is critical, because alpha particles are more dangerous to humans, and this is where the counting comes in. I’m responsible for the safety of the researchers and chemists who are working with cyclotron-produced radiopharmaceuticals, and making sure they’re not inhaling or ingesting alpha particles. Now we could use a Geiger counter to monitor this with low efficiency, but if I can take a swipe and put it into the 600 SL, my efficiencies are great, I can see down to sub-picocurie levels."

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Washington State Public Health Laboratories, USA

Developing the next generation of Liquid Scintillation Counters for super low-level analysis

The State of Washington in the US has legacy environmental contamination caused by nuclear energy, research, and material production. The Washington State Public Health Laboratories (PHL) is a public facility involved in monitoring sites such as the Hanford Nuclear Reservation, which was originally built as part of the Manhattan Project and used for plutonium production during the Cold War.

Following a rigorous tender process with a demanding specification, PHL procured the original Hidex 600 SL. However, following installation a unique fault occurred due to local conditions, which eventually lead to Hidex redesigning the counter to deliver the new 600 SLe. We spoke to Bud Taylor, Supervisor of PHL’s Environmental and Radiation Chemistry Group, and Chemist Danny Bell about the problem and how it was resolved.

Find out what they had to say by clicking the button below.

READ MORE

Documents

Application Notes

  • 600 SL PMT Detector System Identifies True Background With Minimal Random Counts Spread Across MCA

    Download (407.26 kB)

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