The innovative, flexible and compliant flow-through radio-HPLC detector.
LabLogic's innovative Flow-RAM radio-HPLC detector for PET/SPECT is designed to meet the ever increasing demands of the modern laboratory.
Flexible radio-HPLC system
The Flow-RAM radio-HPLC system is available not only as a single radio-HPLC detector but also as a dual instrument, allowing for different parameters to be set for each of the detectors while saving valuable bench space.
With a wide range of detectors suitable for both low and high levels of radioactivity, the Flow-RAM radio HPLC system is an ideal quality control and research instrument.
radio-HPLC detector compliant with regulatory requirements
As with all LabLogic products, the Flow-RAM radio-HPLC detector has been designed to exceed regulatory requirements. Features such as a single power button, coupled with the industry standard Laura for PET QC software offers users the ultimate in compliance.
Controlled by Laura for PET
Flow-RAM control, digital data collection, analysis and reporting can be controlled by Laura for PET, the industry standard SPECT / PET radiochromatography software developed by LabLogic.
To talk about your requirements, get in touch with us now. You can also request a quote or a free demonstration of the Flow-RAM radio HPLC system.
What is the difference between Flow-RAM and Dual Flow-RAM?
The single system is a single radio-HPLC detector. The dual instrument, is two radio-HPLC detectors in one box, each working independently of each other, yet simultaneously.
Why would I choose a Dual Flow-RAM?
The reasons when you would chose a Dual Flow-RAM would be if you wanted to minimise space used by the radio HPLC detectors, and save money when investing in the instrument. For most customers, the Single Flow-RAM meets the requirements.
What happens if a component stops working In the Dual Scan-RAM?
The electronics in the Dual Scan-RAM are separate for radio-TLC and radio-HPLC.
In the unlikely event that one set of electronics develops a fault, the use of the radio-HPLC, or radio-TLC depending upon what happens, would not be affected.
Which radio HPLC systems is the Flow-RAM compatible with?
The Flow-RAM is compatible with all commercially available radio HPLC systems
Can I take the signal from other detectors into Laura and via Flow-RAM?
Yes you can. The Flow-RAM has a built in A-D converter and as such accommodates signals from a range of other detectors such as UV, RID, ECD etc.
Existing Flow-RAM users
Click on the tabs below to find out more about some of our customers and how they are using the Flow-RAM in their facilities.
Universitätsklinikum Essen, Germany
Synthesising and validating [18-F]PARPi
A Logi-CHROM with a Flow-RAM has recently been installed at Essen University Hospital’s Clinic for Nuclear Medicine. The system was procured to complement the clinic’s existing suite of HPLC instruments to increase capacity for a growing team of radiochemists.
Anna Pacelli carries out postdoctoral research at the radiopharmacy into the automation and validation of radiopharmaceuticals for clinical use, specifically [18F]PARPi which was originally developed in the United States but had no automation and scale-up. Anna uses the Logi-CHROM and Flow-RAM for synthesis and optimises the radiolabelling and quality control, explaining why it was chosen over other HPLC solutions.
Click the button below to find out what Anna had to say.
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CHU Grenoble Alpes, France
Validating Analytical Methods in the development of Lutetium-177-PSMA-1
Grenoble University Hospital (CHU Grenoble Alpes) and Grenoble Alpes University (UGA) have used LabLogic’s instruments to submit an Investigational Medicinal Product Dossier (IMPD) for a new radiopharmaceutical labelled with Lutetium-177. A validation dossier for Analytical Methods has been produced to assess the radiochemical purity of 177Lu-PSMA-1 using the Flow-RAM for Radio-High Performance Liquid Chromatography (r-HPLC) and Scan-RAM for Radio-Thin Layer Chromatography (r-TLC).
Click the button below to find out more.
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Memorial Sloan Kettering Cancer Center, USA
Developing PET agents for clincial studies
The Memorial Sloan Kettering Cancer Centre is one of the largest cancer hospitals in the world and focuses on treating patients with advanced modalities and developing novel treatments. Its Radiochemistry and Imaging Sciences Service (RISS, 12 Faculty) in the Department of Radiology is dedicated to developing novel radiolabelled probes of diagnostic and therapeutic applications using LabLogic instruments.
Click the button below to find out more.
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Grenoble Hospital, France
QC of radiolabelled PET molecules after HPLC separation
Two healthcare organisations in Grenoble, France, are using LabLogic’'s Laura radio-chromatography system and instrumentation sourced from the same company to enhance their ability to work closely together.
The nuclear medicine service at Grenoble Hospital has a Flow-RAM radio HPLC detector for PET and SPECT applications, while the nuclear biophysics laboratory of INSERM (France’s national institute of health and medical research) at the city'’s medical college has a Gamma-RAM radio-HPLC detector for soft and intermediate gamma emitters. The laboratory also undertakes PET and SPECT work using the dual-purpose Scan-RAM radio TLC / HPLC scanner.
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Imperial College London, UK
The first UK installation of the Flow-RAM
The Flow-RAM has been installed at Imperial College London in the Faculty of Medicine's Comprehensive Cancer Imaging Centre where it is used for quality checks of radiopharmaceuticals.
Click the button below to find out what Dr Graham Smith had to say.
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