The innovative, flexible and compliant flow-through radio-HPLC detector.

LabLogic's innovative Flow-RAM radio-HPLC detector for PET/SPECT is designed to meet the ever increasing demands of the modern laboratory.

Flexible radio-HPLC system

The Flow-RAM radio-HPLC system is available not only as a single radio-HPLC detector but also as a dual instrument, allowing for different parameters to be set for each of the detectors while saving valuable bench space.

With a wide range of detectors suitable for both low and high levels of radioactivity, the Flow-RAM radio HPLC system is an ideal quality control and research instrument.

radio-HPLC detector compliant with regulatory requirements

As with all LabLogic products, the Flow-RAM radio-HPLC detector has been designed to exceed regulatory requirements. Features such as a single power button, coupled with the industry standard Laura for PET QC software offers users the ultimate in compliance.

Controlled by Laura for PET

Flow-RAM control, digital data collection, analysis and reporting can be controlled by Laura for PET, the industry standard SPECT / PET radiochromatography software developed by LabLogic.

To talk about your requirements, get in touch with us now. You can also request a quote or a free demonstration of the Flow-RAM radio HPLC system.

Custom-Made Lead Shielding

In order to minimize background interference LabLogic provides a range of lead shielding to meet different requirements.

Single Power Button

The single power button and full software control allows only users with an appropriate access level to make changes to the operating parameters.A full audit trail of these changes is recorded.

Intelligent Front End Display

Users are able to view instrument parameters and performance at a glance.

Single USB Connection

Operating parameters such as high voltage, upper and lower level discriminators as well as power supply and data transfer are all achieved through a single USB connection.

Built-in Analog to Digital Converter

This feature coverts analog signals from other detectors such as UV, ECD, etc., into digital for use within Laura for PET. Bringing all signals into one place.

A Range of Detectors

Suitable for PET, SPECT and High Energy Beta radionuclides across a range of radioactivity levels.

Built-in Analog Output

Users can take an analog signal into any third party software.

Laura Radiopharmacy

Scan-RAM control, digital data collection, analysis and reporting. All achieved using the industry standard radiochromatography data system Laura for PET.

Laura Radiopharmacy has been the recognised industry standard software for radiochromatography for more than 20 years. The latest evolution of Laura Radiopharmacy features control of many of the world's leading HPLC and radio detector systems to provide a single point of control for the entire radiochromatography analysis

Laura Radiopharmacy also features:

  • Half-life correction.
  • Seamless interface with PETra™.
  • Scalable solution from stand-alone to enterprise level.
  • GLP and 21 CFR part 11 compliance options.
  • Automatic peak finder.
  • Document management system.
  • Unique summary table function for data comparison.
  • Powerful reporting and analysis tools.

What is the difference between Flow-RAM and Dual Flow-RAM?

The single system is a single radio-HPLC detector. The dual instrument, is two radio-HPLC detectors in one box, each working independently of each other, yet simultaneously.

Why would I choose a Dual Flow-RAM?

The reasons when you would chose a Dual Flow-RAM would be if you wanted to minimize space used by the radio HPLC detectors, and save money when investing in the instrument. For most customers, the Single Flow-RAM meets the requirements.

What happens if a component stops working In the Dual Scan-RAM?

The electronics in the Dual Scan-RAM are separate for radio-TLC and radio-HPLC. In the unlikely event that one set of electronics develops a fault, the use of the radio-HPLC, or radio-TLC depending upon what happens, would not be affected.

Which radio HPLC systems is the Flow-RAM compatible with?

The Flow-RAM is compatible with all commercially available radio HPLC systems

Can I take the signal from other detectors into Laura and via Flow-RAM?

Yes you can. The Flow-RAM has a built in A-D converter and as such accommodates signals from a range of other detectors such as UV, RID, ECD etc.

Existing Flow-RAM users

Click on the tabs below to find out more about some of our customers and how they are using the Flow-RAM in their facilities. 

Universitäts­klinikum Essen, Germany

Synthesising and validating [18-F]PARPi

A Logi-CHROM with a Flow-RAM has recently been installed at Essen University Hospital’s Clinic for Nuclear Medicine. The system was procured to complement the clinic’s existing suite of HPLC instruments to increase capacity for a growing team of radiochemists.

Anna Pacelli carries out postdoctoral research at the radiopharmacy into the automation and validation of radiopharmaceuticals for clinical use, specifically [18F]PARPi which was originally developed in the United States but had no automation and scale-up. Anna uses the Logi-CHROM and Flow-RAM for synthesis and optimizes the radiolabelling and quality control, explaining why it was chosen over other HPLC solutions.

Click the button below to find out what Anna had to say.


CHU Grenoble Alpes, France

Validating Analytical Methods in the development of Lutetium-177-PSMA-1

Grenoble University Hospital (CHU Grenoble Alpes) and Grenoble Alpes University (UGA) have used LabLogic’s instruments to submit an Investigational Medicinal Product Dossier (IMPD) for a new radiopharmaceutical labelled with Lutetium-177. A validation dossier for Analytical Methods has been produced to assess the radiochemical purity of 177Lu-PSMA-1 using the Flow-RAM for Radio-High Performance Liquid Chromatography (r-HPLC) and Scan-RAM for Radio-Thin Layer Chromatography (r-TLC). 

Click the button below to find out more.


Memorial Sloan Kettering Cancer Center, USA

Developing PET agents for clincial studies

The Memorial Sloan Kettering Cancer Center is one of the largest cancer hospitals in the world and focuses on treating patients with advanced modalities and developing novel treatments. Its Radiochemistry and Imaging Sciences Service (RISS, 12 Faculty) in the Department of Radiology is dedicated to developing novel radiolabelled probes of diagnostic and therapeutic applications using LabLogic instruments.

Click the button below to find out more.


Grenoble Hospital, France

QC of radiolabelled PET molecules after HPLC separation

Two healthcare organizations in Grenoble, France, are using LabLogic’'s Laura radio-chromatography system and instrumentation sourced from the same company to enhance their ability to work closely together.

The nuclear medicine service at Grenoble Hospital has a Flow-RAM radio HPLC detector for PET and SPECT applications, while the nuclear biophysics laboratory of INSERM (France’s national institute of health and medical research) at the city'’s medical college has a Gamma-RAM radio-HPLC detector for soft and intermediate gamma emitters. The laboratory also undertakes PET and SPECT work using the dual-purpose Scan-RAM radio TLC / HPLC scanner.

Click the button below to find out more.


Imperial College London, UK

The first UK installation of the Flow-RAM

The Flow-RAM has been installed at Imperial College London in the Faculty of Medicine's Comprehensive Cancer Imaging Center where it is used for quality checks of radiopharmaceuticals.

Click the button below to find out what Dr Graham Smith had to say.



The LabLogic Group will always treat your details with the utmost care and will never sell them to third party companies.

Please choose one of the following:

  • Flow-RAM HPLC radio scanner and analyzer
  • Flow-RAM radio HPLC system
  • Flow-RAM HPLC radio detector